SCO2 Antibody

CATALOG NUMBER: 59-349

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
30 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SCO2
Additional Names:
Protein SCO2 homolog, mitochondrial, SCO2
Protein Accession Number:
O43819
Ncbi Gene Id Number:
9997
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cytochrome c oxidase (COX) catalyzes the transfer ofelectrons from cytochrome c to molecular oxygen, which helps tomaintain the proton gradient across the inner mitochondrialmembrane that is necessary for aerobic ATP production. Human COX isa multimeric protein complex that requires several assemblyfactors; this gene encodes one of the COX asembly factors. Theencoded protein is a metallochaperone that is involved in thebiogenesis of cytochrome c oxidase subunit II. Mutations in thisgene are associated with fatal infantile encephalocardiomyopathy.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Foltopoulou, P.F., et al. Biochim. Biophys. Acta 1802(6):497-508(2010)
Background Reference 3:
Pronicki, M., et al. Eur. J. Paediatr. Neurol. 14(3):253-260(2010)
Background Reference 4:
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-349

List Size:
400 ul

List Price:

$495.00

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