Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis of SDHAF2 in rat liver tissue lysate with SDHAF2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of SDHAF2 in rat liver tissue lysate with SDHAF2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Trial Size

SDHAF2 Antibody

CATALOG NUMBER: 6507

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (93%)
Immunogen:
SDHAF2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SDHAF2.
The immunogen is located within the first 50 amino acids of SDHAF2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SDHAF2 antibody can be used for detection of SDHAF2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Specificity:
SDHAF2 antibody is predicted to not cross-react with other SDHAF protein family members.
Positive Control 1:
Cat. No. 1464 - Rat Liver Tissue Lysate
Purification:
SDHAF2 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgY
physical-state:
Liquid
Buffer:
SDHAF2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
SDHAF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SDHAF2
Additional Names:
SDHAF2 Antibody: PGL2, SDH5, C11orf79, PGL2, Succinate dehydrogenase assembly factor 2, mitochondrial, Succinate dehydrogenase subunit 5, SDH assembly factor 2
Protein Accession Number:
NP_060311
Protein Gi Number:
8923450
Ncbi Gene Id Number:
54949
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SDHAF2 Antibody: SDHAF2 (Succinate dehydrogenase complex assembly factor 2) encodes a mitochondrial protein needed for FAD cofactor attach to the SDH enzyme which plays a critical role in mitochondria. SDHAF2 is a tumor suppressor, but recent evidence suggests that somatic mutations of the SDHAF2 are unlikely to contribute to parathyroid tumor development in sporadic primary hyperparathyroidism.
Background Reference 1:
Hao HX, Khalimonchuk O, Schraders M, et al. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 2009; 325:1139-42.
Background Reference 2:
Burnichon N, Brière JJ, Libé R, et al. SDHA is a tumor suppressor gene causing paraganglioma. Hum. Mol. Genet. 2010; 19:3011-20.
Background Reference 3:
Kunst HP, Rutten MH, de Monnink JP, et al. SDHAF2 (PGL2-SDH5) and hereditary head and neck paraganglioma. Clin. Cancer Res. 2011; 17:247-54
Background Reference 4:
Starker LF, Delgado-Verdugo A, Udelsman R, et al. Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism. Endocrine 2010; 38:397-401.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

6507

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369