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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

SDHB Antibody

CATALOG NUMBER: 60-810

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig
Immunogen:
This SDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SDHB
Additional Names:
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1
Protein Accession Number:
P21912
Protein Gi Number:
20455488
Ncbi Gene Id Number:
6390
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Complex II of the respiratory chain, which is specificallyinvolved in the oxidation of succinate, carries electrons from FADHto CoQ. The complex is composed of four nuclear-encoded subunitsand is localized in the mitochondrial inner membrane. Theiron-sulfur subunit is highly conserved and contains threecysteine-rich clusters which may comprise the iron-sulfur centersof the enzyme. Sporadic and familial mutations in this gene resultin paragangliomas and pheochromocytoma, and support a link betweenmitochondrial dysfunction and tumorigenesis.
Background Reference 1:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Cerecer-Gil, N.Y., et al. Clin. Cancer Res. 16(16):4148-4154(2010)
Background Reference 4:
Schimke, R.N., et al. Am. J. Med. Genet.152A (6), 1531-1535 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-810

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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