SEC23B Antibody

CATALOG NUMBER: 60-031

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SEC23B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the C-terminal region of human SEC23B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
86 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SEC23B
Additional Names:
Protein transport protein Sec23B, SEC23-related protein B, SEC23B
Protein Accession Number:
Q15437
Protein Gi Number:
20141794
Ncbi Gene Id Number:
10483
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the SEC23subfamily of the SEC23/SEC24 family, which is involved in vesicletrafficking. The encoded protein has similarity to yeast Sec23pcomponent of COPII. COPII is the coat protein complex responsiblefor vesicle budding from the ER. The function of this gene producthas been implicated in cargo selection and concentration. Multiplealternatively spliced transcript variants have been identified inthis gene.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Fermo, E., et al. Blood Cells Mol. Dis. 45(1):20-22(2010)
Background Reference 3:
Bianchi, P., et al. Hum. Mutat. 30(9):1292-1298(2009)
Background Reference 4:
Schwarz, K., et al. Nat. Genet. 41(8):936-940(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-031

List Size:
400 ul

List Price:

$495.00

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