SEC23IP Antibody

CATALOG NUMBER: 57-779

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
111 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SEC23IP
Additional Names:
SEC23-interacting protein, p125, SEC23IP
Protein Accession Number:
Q9Y6Y8
Protein Gi Number:
55584014
Ncbi Gene Id Number:
11196
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
COPII-coated vesicles are involved in protein transportfrom the endoplasmic reticulum to the Golgi apparatus. The proteinencoded by this gene was identified by its interaction with a mouseprotein similar to yeast Sec23p, an essential component of theCOPII. This protein shares significant similarity withphospholipid-modifying proteins, especially phosphatidic acidpreferring-phospholipase A1. Overexpression of this protein hasbeen shown to cause disorganization of the endoplasmicreticulum-Golgi intermediate compartment and Golgi apparatus, whichsuggests its role in the early secretory pathway. [provided byRefSeq].
Background Reference 1:
Ong, Y.S., et al. J. Cell Biol. 190(3):331-345(2010)
Background Reference 2:
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background Reference 3:
Li, H., et al. J. Biol. Chem. 281(21):14748-14755(2006)
Background Reference 4:
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-779

List Size:
400 ul

List Price:

$495.00

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