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Western blot analysis in mouse liver tissue lysates (35ug/lane).
SEC61B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in mouse liver tissue lysates (35ug/lane).

SEC61B Antibody

CATALOG NUMBER: 58-090

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This SEC61B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the Central region of human SEC61B.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
10 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SEC61B
Additional Names:
Protein transport protein Sec61 subunit beta, SEC61B
Protein Accession Number:
P60468
Protein Gi Number:
42560366
Ncbi Gene Id Number:
10952
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Sec61 complex is the central component of the proteintranslocation apparatus of the endoplasmic reticulum (ER) membrane.Oligomers of the Sec61 complex form a transmembrane channel whereproteins are translocated across and integrated into the ERmembrane. This complex consists of three membrane proteins- alpha,beta, and gamma. This gene encodes the beta-subunit protein. TheSec61 subunits are also observed in the post-ER compartment,suggesting that these proteins can escape the ER and recycle back.There is evidence for multiple polyadenylated sites for thistranscript.
Background Reference 1:
Liao, H.J., et al. Cancer Res. 69(15):6179-6183(2009)
Background Reference 2:
Wang, B., et al. Cell 133(6):1080-1092(2008)
Background Reference 3:
Liao, H.J., et al. Mol. Biol. Cell 18(3):1064-1072(2007)
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-090

List Size:
400 ul

List Price:

$495.00

Datasheet
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