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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

SENP5 Antibody

CATALOG NUMBER: 57-708

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Immunogen:
This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
87 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SENP5
Additional Names:
Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, SENP5
Protein Accession Number:
Q96HI0
Protein Gi Number:
296452962
Ncbi Gene Id Number:
205564
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The reversible posttranslational modification of proteinsby the addition of small ubiquitin-like SUMO proteins (see SUMO1;MIM 601912) is required for numerous biologic processes.SUMO-specific proteases, such as SENP5, are responsible for theinitial processing of SUMO precursors to generate a C-terminaldiglycine motif required for the conjugation reaction. They alsohave isopeptidase activity for the removal of SUMO from highmolecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed16738315]).
Background Reference 1:
Yun, C., et al. J. Cell Biol. 183(4):589-595(2008)
Background Reference 2:
Ding, X., et al. Oncol. Rep. 20(5):1041-1045(2008)
Background Reference 3:
Gong, L., et al. J. Biol. Chem. 281(23):15869-15877(2006)
Background Reference 4:
Di Bacco, A., et al. Mol. Cell. Biol. 26(12):4489-4498(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-708

List Size:
400 ul

List Price:

$495.00

Datasheet
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