SEPT12 Antibody

CATALOG NUMBER: 60-448

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SEPT12
Additional Names:
Septin-12, SEPT12
Protein Accession Number:
Q8IYM1
Protein Gi Number:
74750767
Ncbi Gene Id Number:
124404
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Septins, such as SEPT12, are conserved GTP-bindingproteins that function as dynamic, regulatable scaffolds for therecruitment of other proteins. They are involved in membranedynamics, vesicle trafficking, apoptosis, and cytoskeletonremodeling, as well as infection, neurodegeneration, and neoplasia(Hall et al., 2005 [PubMed 15915442]).
Background Reference 1:
Lin, Y.H., et al. Am. J. Pathol. 174(5):1857-1868(2009)
Background Reference 2:
Ding, X., et al. Mol. Cells 25(3):385-389(2008)
Background Reference 3:
Ding, X., et al. J. Biochem. Mol. Biol. 40(6):973-978(2007)
Background Reference 4:
Lamesch, P., et al. Genomics 89(3):307-315(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-448

List Size:
400 ul

List Price:

$495.00

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