SEPT6 Antibody

CATALOG NUMBER: 60-054

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
50 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SEPT6
Additional Names:
Septin-6, SEPT6, KIAA0128, SEP2
Protein Accession Number:
Q14141
Protein Gi Number:
20178343
Ncbi Gene Id Number:
23157
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the septin family of GTPases.Members of this family are required for cytokinesis. One version ofpediatric acute myeloid leukemia is the result of a reciprocaltranslocation between chromosomes 11 and X, with the breakpointassociated with the genes encoding the mixed-lineage leukemia andseptin 2 proteins. This gene encodes four transcript variantsencoding three distinct isoforms. An additional transcript varianthas been identified, but its biological validity has not beendetermined.
Background Reference 1:
Ding, X., et al. J. Biochem. Mol. Biol. 40(6):973-978(2007)
Background Reference 2:
Sirajuddin, M., et al. Nature 449(7160):311-315(2007)
Background Reference 3:
Kremer, B.E., et al. Cell 130(5):837-850(2007)
Background Reference 4:
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-054

List Size:
400 ul

List Price:

$495.00

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