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The purity of rh Serpin E2 /PN1 /GDN was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh Serpin E2 /PN1 /GDN was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Serpin E2 Recombinant Protein

CATALOG NUMBER: 96-683

Tested Applications:
WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Ser 20 - Pro 397
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
42.7 kDa
Biological Activity:
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca - RPKPVE - Nval - WRK(Dnp) - NH2.
Purity:
>92% as determined by SDS-PAGE.
Physical State:
Lyophilized
Buffer:
20 mM NaAc, 100 mM NaCl, PH6.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SERPINE2
Additional Names:
SERPINE2, Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Serpin E2, SerpinE2, PI7
Protein Accession Number:
P07093-2
Ncbi Gene Id Number:
5270
Background:
SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.
Background Reference 1:
Gloor S.M., et al., 1986, Cell 47:687-693.
Background Reference 2:
Scott R.W., et al., 1985, J. Biol. Chem. 260:7029-7034.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-683

List Size:
0.025 mg

List Price:

$495.00

Out of stock

Datasheet
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