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Human Serpin A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human Serpin A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SERPINA3 Recombinant Protein

CATALOG NUMBER: 96-684

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
His 24 - Ala 423
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
46 kDa
Biological Activity:
Measured by its ability to inhibit chymotrypsin cleavage of a fluorogenic peptide substrate MCA-RPKPVE-Nval-WRK(Dnp)-NH2. The IC50 value is <6 nM.
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
20 mM HEPES, 150 mM NaCl, pH 7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SERPINA3
Additional Names:
SERPINA3, ACT, AACT, GIG24, GIG25
Protein Accession Number:
AAH03559
Ncbi Gene Id Number:
12
Background:
Serpin A3 is also known as Alpha-1-antichymotrypsin (ACT or AACT), Cell growth-inhibiting gene 24/25 protein, which belongs to the serpin family. Serpin A3 can bind DNA. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Background Reference 1:
Rubin H., et al., 1990, J. Biol. Chem. 265:1199-1207.
Background Reference 2:
Kroczynska B., et al., 2004, J. Biol. Chem. 279:11432-11443.
Background Reference 3:
Liu T., et al., 2005, J. Proteome Res. 4:2070-2080.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-684

List Size:
0.05 mg

List Price:

$540.00

Datasheet
Shipping Info

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