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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

SERPINB8 Antibody

CATALOG NUMBER: 60-851

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SERPINB8
Additional Names:
Serpin B8, Cytoplasmic antiproteinase 2, CAP-2, CAP2, Peptidase inhibitor 8, PI-8, SERPINB8, PI8
Protein Accession Number:
P50452
Protein Gi Number:
212276474
Ncbi Gene Id Number:
5271
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The superfamily of high molecular weight serine proteinaseinhibitors (serpins) regulate a diverse set of intracellular andextracellular processes such as complement activation,fibrinolysis, coagulation, cellular differentiation, tumorsuppression, apoptosis, and cell migration. Serpins arecharacterized by well-conserved a tertiary structure that consistsof 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989[PubMed 2690952]). A critical portion of the molecule, the reactivecenter loop connects beta sheets A and C. Protease inhibitor-8(PI8; SERPINB8) is a member of the ov-serpin subfamily, which,relative to the archetypal serpin PI1 (MIM 107400), ischaracterized by a high degree of homology to chicken ovalbumin,lack of N- and C-terminal extensions, absence of a signal peptide,and a serine rather than an asparagine residue at the penultimateposition (summary by Bartuski et al., 1997 [PubMed9268635]).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
de Koning, P.J., et al. Pancreas 38(4):461-467(2009)
Background Reference 3:
Luke, M.M., et al. Stroke 40(2):363-368(2009)
Background Reference 4:
Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-851

List Size:
400 ul

List Price:

$495.00

Datasheet
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