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Western blot analysis of lysate from SH-SY5Y cell line, using SERPINI1 Antibody at 1:1000 at each lane.
SERPINI1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Confocal immunofluorescent analysis of SERPINI1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Western blot analysis of lysate from SH-SY5Y cell line, using SERPINI1 Antibody at 1:1000 at each lane.

SERPINI1 Antibody

CATALOG NUMBER: 55-159

Clonality:
Polyclonal
Tested Applications:
Flow, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SERPINI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human SERPINI1.
Conjugate:
Unconjugated
Tested Applications:
Flow, IF, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SERPINI1
Additional Names:
Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12
Protein Accession Number:
Q99574
Protein Gi Number:
3183087
Ncbi Gene Id Number:
5274
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the serpin superfamily ofserine proteinase inhibitors. The protein is primarily secreted byaxons in the brain, and preferentially reacts with and inhibitstissue-type plasminogen activator. It is thought to play a role inthe regulation of axonal growth and the development of synapticplasticity. Mutations in this gene result in familialencephalopathy with neuroserpin inclusion bodies (FENIB), which isa dominantly inherited form of familial encephalopathy and epilepsycharacterized by the accumulation of mutant neuroserpin polymers.Multiple alternatively spliced variants, encoding the same protein,have been identified.
Background Reference 1:
Takehara, S., et al. J. Mol. Biol. 403(5):751-762(2010)
Background Reference 2:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 3:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Background Reference 4:
Davies, M.J., et al. J. Biol. Chem. 284(27):18202-18209(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-159

List Size:
400 ul

List Price:

$495.00

Datasheet
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