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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

SERPINI2 Antibody

CATALOG NUMBER: 59-363

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SERPINI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human SERPINI2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SERPINI2
Additional Names:
Serpin I2, Myoepithelium-derived serine protease inhibitor, Pancpin, Pancreas-specific protein TSA2004, Peptidase inhibitor 14, PI-14, SERPINI2, MEPI, PI14
Protein Accession Number:
O75830
Ncbi Gene Id Number:
5276
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the serineprotease inhibitor (serpin) superfamily made up of proteins whichplay central roles in the regulation of a wide variety ofphysiological processes, including coagulation, fibrinolysis,development, malignancy and inflammation. The gene product may havea role in a growth-control, possibly growth-suppressing pathwayand, when impaired, may be involved in pancreatic carcinogenesis.The protein is a member of the plasminogen activator inhibitor-1family, a subset of the serpin superfamily whose members act astissue-specific tPA inhibitors. Two alternatively splicedtranscript variants encoding distinct protein isoforms have beenfound for this gene.
Background Reference 1:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 2:
Lim, J., et al. Cell 125(4):801-814(2006)
Background Reference 3:
Chang, W.S., et al. Genes Chromosomes Cancer 29(3):240-255(2000)
Background Reference 4:
Xiao, G., et al. Proc. Natl. Acad. Sci. U.S.A. 96(7):3700-3705(1999)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-363

List Size:
400 ul

List Price:

$495.00

Datasheet
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