SF3A2 Antibody

CATALOG NUMBER: 60-831

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SF3A2
Additional Names:
Splicing factor 3A subunit 2, SF3a66, Spliceosome-associated protein 62, SAP 62, SF3A2, SAP62
Protein Accession Number:
Q15428
Protein Gi Number:
20141793
Ncbi Gene Id Number:
8175
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes subunit 2 of the splicing factor 3aprotein complex. The splicing factor 3a heterotrimer includessubunits 1, 2 and 3 and is necessary for the in vitro conversion of15S U2 snRNP into an active 17S particle that performs pre-mRNAsplicing. Subunit 2 interacts with subunit 1 through itsamino-terminus while the single zinc finger domain of subunit 2plays a role in its binding to the 15S U2 snRNP. Subunit 2 may alsofunction independently of its RNA splicing function as amicrotubule-binding protein.
Background Reference 1:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 2:
Tanackovic, G., et al. Mol. Biol. Cell 16(3):1366-1377(2005)
Background Reference 3:
Nesic, D., et al. J. Cell. Sci. 117 (PT 19), 4423-4433 (2004) :
Background Reference 4:
Takenaka, K., et al. Biochem. J. 382 (PT 1), 223-230 (2004) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-831

List Size:
400 ul

List Price:

$495.00

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