SGCA Antibody

CATALOG NUMBER: 59-032

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SGCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-266 amino acids from the Central region of human SGCA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SGCA
Additional Names:
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2
Protein Accession Number:
Q16586
Ncbi Gene Id Number:
6442
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a component of thedystrophin-glycoprotein complex (DGC), which is critical to thestability of muscle fiber membranes and to the linking of the actincytoskeleton to the extracellular matrix. Its expression is thoughtto be restricted to striated muscle. Mutations in this gene resultin type 2D autosomal recessive limb-girdle muscular dystrophy.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Mendell, J.R., et al. Ann. Neurol. 68(5):629-638(2010)
Background Reference 2:
Fernandez, K., et al. Am. J. Pathol. 176(1):416-434(2010)
Background Reference 3:
Klinge, L., et al. Neuromuscul. Disord. 18(12):934-941(2008)
Background Reference 4:
Delgado-Olguin, P., et al. Biochim. Biophys. Acta 1779(1):74-80(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-032

List Size:
400 ul

List Price:

$495.00

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