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Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.
Antibody used in WB on Human Heart at 0.2-1 ug/ml.

SGCB Antibody

CATALOG NUMBER: 25-941

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SGCB.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SGCB antibody can be used for detection of SGCB by ELISA at 1:312500. SGCB antibody can be used for detection of SGCB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Predicted Molecular Weight:
35 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SGCB antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SGCB
Additional Names:
SGCB, A3b, LGMD2E, SGC
Protein Accession Number:
NP_000223
Protein Gi Number:
4506913
Ncbi Gene Id Number:
6443
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).
Background Reference 1:
Draviam, R.A., (2006) Muscle Nerve 34 (6), 691-701.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-941

List Size:
100 ul

List Price:

$519.00

Datasheet
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