SGCD Antibody

CATALOG NUMBER: 58-270

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This SGCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human SGCD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SGCD
Additional Names:
Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD
Protein Accession Number:
Q92629
Protein Gi Number:
212276471
Ncbi Gene Id Number:
6444
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is one of the four knowncomponents of the sarcoglycan complex, which is a subcomplex of thedystrophin-glycoprotein complex (DGC). DGC forms a link between theF-actin cytoskeleton and the extracellular matrix. This protein isexpressed most abundantly in skeletal and cardiac muscle. Mutationsin this gene have been associated with autosomal recessivelimb-girdle muscular dystrophy and dilated cardiomyopathy.Alternatively spliced transcript variants encoding distinctisoforms have been observed for this gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
Background Reference 4:
Ordonez-Razo, R.M., et al. Genet Test Mol Biomarkers 14(2):237-240(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-270

List Size:
400 ul

List Price:

$495.00

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