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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
SGEF Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

SGEF Antibody

CATALOG NUMBER: 56-989

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
97 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF26
Additional Names:
Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor, ARHGEF26, SGEF
Protein Accession Number:
Q96DR7
Protein Gi Number:
317373555
Ncbi Gene Id Number:
26084
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
Background Reference 1:
Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
Background Reference 2:
Ellerbroek, S.M., et al. Mol. Biol. Cell 15(7):3309-3319(2004)
Background Reference 3:
Qi, H., et al. Endocrinology 144(5):1742-1752(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-989

List Size:
400 ul

List Price:

$495.00

Datasheet
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