SH3BGR Antibody

CATALOG NUMBER: 58-788

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SH3BGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human SH3BGR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SH3BGR
Additional Names:
SH3 domain-binding glutamic acid-rich protein, SH3BGR protein, 21-glutamic acid-rich protein, 21-GARP, SH3BGR
Protein Accession Number:
P55822
Protein Gi Number:
215274184
Ncbi Gene Id Number:
6450
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. SH3 domain binding glutamic acid-rich protein (SH3BGR), also designated 21-glutamic acid-rich protein (21-GARP), is a 239-amino acid protein differentially expressed in heart and skeletal muscle. Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure. SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.
Background Reference 1:
Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :
Background Reference 2:
Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
Background Reference 3:
Sandri, C., et al. Hum. Genet. 114(5):517-519(2004)
Background Reference 4:
Jiang, L.Q., et al. Hypertens. Res. 25(4):647-652(2002)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-788

List Size:
400 ul

List Price:

$495.00

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