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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

SH3BP1 Antibody

CATALOG NUMBER: 58-823

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
76 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SH3BP1
Additional Names:
SH3 domain-binding protein 1, 3BP-1, SH3BP1
Protein Accession Number:
Q9Y3L3
Protein Gi Number:
51338841
Ncbi Gene Id Number:
23616
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
Background Reference 1:
Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
Background Reference 2:
Scott, M.P., et al. J. Biol. Chem. 277(31):28238-28246(2002)
Background Reference 3:
Dunham, I., et al. Nature 402(6761):489-495(1999)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-823

List Size:
400 ul

List Price:

$495.00

Datasheet
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