SH3BP2 Antibody

CATALOG NUMBER: 27-092

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SH3BP2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SH3BP2 antibody can be used for detection of SH3BP2 by ELISA at 1:1562500. SH3BP2 antibody can be used for detection of SH3BP2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
721_B Cell Lysate
Predicted Molecular Weight:
62 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SH3BP2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SH3BP2
Additional Names:
SH3BP2, 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2
Protein Accession Number:
NP_003014
Protein Gi Number:
170014703
Ncbi Gene Id Number:
6452
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
Background Reference 1:
Idowu, B.D., (2008) Br J Oral Maxillofac Surg 46 (3), 229-230.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-092

List Size:
100 ul

List Price:

$519.00

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