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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
Western blot analysis in mouse bladder tissue lysates (35ug/lane).

SHANK2 Antibody

CATALOG NUMBER: 56-643

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
159 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SHANK2
Additional Names:
SH3 and multiple ankyrin repeat domains protein 2, Shank2, Cortactin-binding protein 1, CortBP1, Proline-rich synapse-associated protein 1, SHANK2, CORTBP1, KIAA1022, PROSAP1
Protein Accession Number:
Q9UPX8
Protein Gi Number:
254763402
Ncbi Gene Id Number:
22941
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is a member of the Shankfamily of synaptic proteins that may function as molecularscaffolds in the postsynaptic density (PSD). Shank proteins containmultiple domains for protein-protein interaction, including ankyrinrepeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alphamotif domain, and a proline-rich region. This particular familymember contains a PDZ domain, a consensus sequence for cortactinSH3 domain-binding peptides and a sterile alpha motif. Thealternative splicing demonstrated in Shank genes has been suggestedas a mechanism for regulating the molecular structure of Shank andthe spectrum of Shank-interacting proteins in the PSDs of adult anddeveloping brain. Two alternative splice variants, encodingdistinct isoforms, are reported. Additional splice variants existbut their full-length nature has not been determined. [provided byRefSeq].
Background Reference 1:
Pinto, D., et al. Nature 466(7304):368-372(2010)
Background Reference 2:
Berkel, S., et al. Nat. Genet. 42(6):489-491(2010)
Background Reference 3:
Lee, J.S., et al. J. Biol. Chem. 285(11):8104-8113(2010)
Background Reference 4:
Wu, C., et al. Proteomics 7(11):1775-1785(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-643

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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