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Western blot analysis of lysed extracts from 293 cells using SHP-1 (Ab-536).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-1 (Ab-536).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed MCF cells using SHP-1 (Ab-536).
Western blot analysis of lysed extracts from 293 cells using SHP-1 (Ab-536).

SHP 1 (Ab 536) Antibody

CATALOG NUMBER: 79-413

Clonality:
Polyclonal
Tested Applications:
IF, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
SHP-1 (Ab-536) antibody was raised against a peptide sequence around aa.534~538 (S-E-Y-G-N) derived from Human SHP-1.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Specificity:
This antibody detects endogenous level of total SHP-1 protein.
Predicted Molecular Weight:
68 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
PTPN6
Additional Names:
HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, BLIMP1, 70Z-SHP, EC 3.1.3.48, HCP, Hematopoietic cell protein-tyrosine phosphatase
Protein Accession Number:
NP_002822.2
Protein Gi Number:
18104989
Ncbi Gene Id Number:
5777
Background:
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
Background Reference 1:
Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95 (7): 3845-3850. Timms JF, et al. (1998) Mol Cell Biol; 18 (7): 3838-3850. Kanagasundaram V, et al. (1999) Mol Cell Biol; 19 (6): 4079-4092. Hauck CR, et al. (1999) Infect Immun; 67 (10): 5490-5494.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-413

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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