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Western blot testing of human samples with SIN1 antibody at 1ug/ml.
Western blot testing of human samples with SIN1 antibody at 1ug/ml.

SIN1 Antibody

CATALOG NUMBER: 33-014

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
Purification:
Protein A purified antibody
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Storage Conditions:
Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
MAPKAP1
Additional Names:
MAPKAP1 Antibody: MIP1, SIN1, JC310, SIN1b, SIN1g, MIP1, Target of rapamycin complex 2 subunit MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, TORC2 subunit MAPKAP1
Ncbi Gene Id Number:
79109
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-014

List Size:
100 ug

List Price:

$520.00

Datasheet
Shipping Info

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