SIRT5 Antibody

CATALOG NUMBER: 27-581

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIRT5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
SIRT5 antibody can be used for detection of SIRT5 by ELISA at 1:312500. SIRT5 antibody can be used for detection of SIRT5 by western blot at 2.0/mL.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
32 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SIRT5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SIRT5
Additional Names:
SIRT5, SIR2L5
Protein Accession Number:
NP_112534
Protein Gi Number:
13787215
Ncbi Gene Id Number:
23408
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.
Background Reference 1:
Frye, R.A. (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-581

List Size:
100 ul

List Price:

$519.00

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