SKAP1 Antibody

CATALOG NUMBER: 60-148

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SKAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human SKAP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SKAP1
Additional Names:
Src kinase-associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, SKAP-55, pp55, SKAP1, SCAP1, SKAP55
Protein Accession Number:
Q86WV1
Protein Gi Number:
269849660
Ncbi Gene Id Number:
8631
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a T cell adaptor protein, a class ofintracellular molecules with modular domains capable of recruitingadditional proteins but that exhibit no intrinsic enzymaticactivity. The encoded protein contains a unique N-terminal regionfollowed by a PH domain and C-terminal SH3 domain. Along with theadhesion and degranulation-promoting adaptor protein, the encodedprotein plays a critical role in inside-out signaling by couplingT-cell antigen receptor stimulation to the activation of integrins.
Background Reference 1:
Goode, E.L., et al. Nat. Genet. 42(10):874-879(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Raab, M., et al. Immunity 32(4):541-556(2010)
Background Reference 4:
Lehmann, R., et al. Proteomics 9(23):5288-5295(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-148

List Size:
400 ul

List Price:

$495.00

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