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Immunohistochemistry of SLAIN2 in human testis with SLAIN2 antibody at 5 μg/mL.
Immunohistochemistry of SLAIN2 in human testis with SLAIN2 antibody at 5 μg/mL.
Trial Size

SLAIN2 Antibody

CATALOG NUMBER: 5471

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC-P
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (93%)
Immunogen:
SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2.
The immunogen is located within amino acids 70 - 120 of SLAIN2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC-P
Application Note:
SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Specificity:
SLAIN2 antibody is predicted not to cross-react with SLAIN1.
Positive Control 1:
Cat. No. 11-701 - Human Testis Tissue Slide
Predicted Molecular Weight:
64 kDa
Purification:
SLAIN2 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
SLAIN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLAIN2
Additional Names:
SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2
Protein Accession Number:
AAH40993
Protein Gi Number:
26454712
Ncbi Gene Id Number:
57606
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
Background Reference 1:
Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.
Background Reference 2:
van der Vaart B, Manatschal C, Grigoriev I, et al. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J. Cell Biol. 2011; 193:1083-99.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5471

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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