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Western blot analysis in T47D cell line lysates (35ug/lane).
Western blot analysis in T47D cell line lysates (35ug/lane).

SLAMF6 Antibody

CATALOG NUMBER: 58-240

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SLAMF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human SLAMF6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLAMF6
Additional Names:
SLAM family member 6, Activating NK receptor, NK-T-B-antigen, NTB-A, CD352, SLAMF6, KALI
Protein Accession Number:
Q96DU3
Protein Gi Number:
205830927
Ncbi Gene Id Number:
114836
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a type I transmembraneprotein, belonging to the CD2 subfamily of the immunoglobulinsuperfamily. This encoded protein is expressed on Natural killer(NK), T, and B lymphocytes. It undergoes tyrosine phosphorylationand associates with the Src homology 2 domain-containing protein(SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs).It functions as a coreceptor in the process of NK cell activation.It can also mediate inhibitory signals in NK cells from X-linkedlymphoproliferative patients. Alternative splicing results inmultiple transcript variants encoding distinct isoforms.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 4:
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-240

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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