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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
Western blot analysis of SLC11A1 Antibody in CEM cell line lysates (35ug/lane)
Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.

SLC11A1 Antibody

CATALOG NUMBER: 63-497

Clonality:
Polyclonal
Tested Applications:
IF, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SLC11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-276 amino acids from the Central region of human SLC11A1.
Conjugate:
Unconjugated
Tested Applications:
IF, WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLC11A1
Additional Names:
Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1, SLC11A1, LSH, NRAMP, NRAMP1
Protein Accession Number:
P49279
Protein Gi Number:
1352521
Ncbi Gene Id Number:
6556
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Background Reference 1:
Jin,J., et.al., Zhongguo Dang Dai Er Ke Za Zhi 11 (4), 283-287 (2009)
Background Reference 2:
Liu,J., et.al., Am. J. Hum. Genet. 56 (4), 845-853 (1995)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-497

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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