SLC1A5 Recombinant Protein

CATALOG NUMBER: 11-460

Tested Applications:
WB
Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Gln 154 - Gln 224
Fusion Tag:
His Tag & TrxA Tag
Tested Applications:
WB
Application Note:
This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag. The protein has a calculated MW of 22.5 kDa. The protein migrates as 24 KDa under reducing (R) condition (SDS-PAGE).
Predicted Molecular Weight:
22.5 kDa
Purity:
>90% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
SLC1A5
Additional Names:
ASCT2,M7V1,RDR,RDRC,ATB(0),AAAT,ASCT2M7VS1,M7V1ATBO,R16,RD114,RDRCFLJ31068
Protein Accession Number:
NP_005619.1
Ncbi Gene Id Number:
6510
Background:
Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).
Background Reference 1:
Kekuda R., et al. 1996, J Biol Chem., 271(31), 18657-61.
Background Reference 2:
Blond JL., et al. 2000, J Virol., 74(7), 3321-9.
Background Reference 3:
Sugimoto J., et al. 2017,Sci Rep., 3,1462.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-460

List Size:
0.1 mg

List Price:

$577.00

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