SLC24A3 Antibody

CATALOG NUMBER: 58-449

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SLC24A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SLC24A3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
72 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLC24A3
Additional Names:
Sodium/potassium/calcium exchanger 3, Na(+)/K(+)/Ca(2+)-exchange protein 3, Solute carrier family 24 member 3, SLC24A3, NCKX3
Protein Accession Number:
Q9HC58
Protein Gi Number:
116242671
Ncbi Gene Id Number:
57419
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Plasma membrane sodium/calcium exchangers are an importantcomponent of intracellular calcium homeostasis and electricalconduction. Potassium-dependent sodium/calcium exchangers such asSLC24A3 are believed to transport 1 intracellular calcium and 1potassium ion in exchange for 4 extracellular sodium ions (Kraev etal., 2001 [PubMed 11294880]).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Cheng, Y.C., et al. Circ Cardiovasc Genet 2(4):329-337(2009)
Background Reference 3:
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Background Reference 4:
Kraev, A., et al. J. Biol. Chem. 276(25):23161-23172(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-449

List Size:
400 ul

List Price:

$495.00

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