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Western blot analysis of Slc37A2 in mouse spleen tissue lysate with Slc37A2 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Immunohistochemistry of Slc37A2 in rat spleen tissue with Slc37A2 antibody at 5 μg/mL.
Immunofluorescence of Slc37A2 in rat spleen tissue with Slc37A2 antibody at 20 μg/mL.
Western blot analysis of Slc37A2 in mouse spleen tissue lysate with Slc37A2 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Trial Size

Slc37A2 Antibody

CATALOG NUMBER: 5647

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Slc37A2 antibody was raised against a 15 amino acid synthetic peptide near the center of human Slc37A2.
The immunogen is located within amino acids 230 - 280 of Slc37A2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
Slc37A2 antibody can be used for detection of Slc37A2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1406 - Mouse Spleen Tissue Lysate
Purification:
Slc37A2 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Slc37A2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
Slc37A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLC37A2
Additional Names:
Slc37A2 Antibody: pp11662, SPX2, Sugar phosphate exchanger 2, Solute carrier family 37 member 2
Protein Accession Number:
NP_938018
Protein Gi Number:
38093649
Ncbi Gene Id Number:
219855
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Slc37A2 Antibody: The Slc37 gene family consists of four members which have 10-12 predicted transmembrane domains and belong to the sugar-phosphate transporter superfamily. Recent experiments have demonstrated that Slc37A2 is a macrophage-specific gene selectively expressed in obese white adipose tissue. Its transcript is also expressed in spleen and thymus and the cell lines RAW264.7 and THP-1. Compared to wild-type mice, Slc37A2 mRNA is expressed at nine-fold higher levels in abdominal epididymal fat deposits of ob/ob mice, suggesting that it may be required to limit the contribution of macrophages to the inflammatory state present in obesity. Slc37A2 protein is post-translationally modified with the addition of N-linked glycans and migrates as a heterogeneous species of 50-75kDa.
Background Reference 1:
Bartolini L and Antonarakis SE. The human sugar-phosphate/phosphate exchanger family SLC37. Eur. J. Physiol.2004; 447-780-3.
Background Reference 2:
Kim JY, Tillison K, Zhou S, et al. The major facilitator superfamily member Slc37a2 is a novel macrophage-specific gene selectively expressed in obese white adipose tissue. Am. J. Physiol. Endocrinol. Metab.2007; 293:E110-20.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5647

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

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