SMC2 Antibody

CATALOG NUMBER: 61-428

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SMC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1166-1197 amino acids from the C-terminal region of human SMC2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
136 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SMC2
Additional Names:
Structural maintenance of chromosomes protein 2, SMC protein 2, SMC-2, Chromosome-associated protein E, hCAP-E, XCAP-E homolog, SMC2, CAPE, SMC2L1
Protein Accession Number:
O95347
Ncbi Gene Id Number:
10592
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Background Reference 1:
Schmiesing,J.A., Proc. Natl. Acad. Sci. U.S.A. 95 (22), 12906-12911 (1998)
Background Reference 2:
Ham,M.F., Cancer Sci. 98 (7), 1041-1047 (2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-428

List Size:
400 ul

List Price:

$495.00

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