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Western blot analysis in human placenta tissue lysates (35ug/lane).
Western blot analysis of SNAP23 using rabbit polyclonal SNAP23 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNAP23 gene.
SNAP23 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in human placenta tissue lysates (35ug/lane).

SNAP23 Antibody

CATALOG NUMBER: 57-840

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SNAP23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the C-terminal region of human SNAP23.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNAP23
Additional Names:
Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23
Protein Accession Number:
O00161
Ncbi Gene Id Number:
8773
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Specificity of vesicular transport is regulated, in part,by the interaction of a vesicle-associated membrane protein termedsynaptobrevin/VAMP with a target compartment membrane proteintermed syntaxin. These proteins, together with SNAP25(synaptosome-associated protein of 25 kDa), form a complex whichserves as a binding site for the general membrane fusion machinery.Synaptobrevin/VAMP and syntaxin are believed to be involved invesicular transport in most, if not all cells, while SNAP25 ispresent almost exclusively in the brain, suggesting that aubiquitously expressed homolog of SNAP25 exists to facilitatetransport vesicle/target membrane fusion in other tissues. Theprotein encoded by this gene is structurally and functionallysimilar to SNAP25 and binds tightly to multiple syntaxins andsynaptobrevins/VAMPs. It is an essential component of the highaffinity receptor for the general membrane fusion machinery and isan important regulator of transport vesicle docking and fusion. Twoalternative transcript variants encoding different protein isoformshave been described for this gene.
Background Reference 1:
Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)
Background Reference 2:
Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)
Background Reference 3:
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Background Reference 4:
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-840

List Size:
400 ul

List Price:

$495.00

Datasheet
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