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Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Antibody used in WB on Human Heart at 0.2-1 ug/ml.

SNUPN Antibody

CATALOG NUMBER: 25-631

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNUPN.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SNUPN antibody can be used for detection of SNUPN by ELISA at 1:62500. SNUPN antibody can be used for detection of SNUPN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Predicted Molecular Weight:
41 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SNUPN antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SNUPN
Additional Names:
SNUPN, KPNBL, RNUT1, Snurportin1
Protein Accession Number:
NP_005692
Protein Gi Number:
5031833
Ncbi Gene Id Number:
10073
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Background Reference 1:
Ospina, J.K., (2005) Mol. Biol. Cell 16 (10), 4660-4671.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-631

List Size:
100 ul

List Price:

$519.00

Datasheet
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