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Western blot analysis in A375 cell line lysates (35ug/lane).
Western blot analysis in A375 cell line lysates (35ug/lane).

SNUPN Antibody

CATALOG NUMBER: 58-602

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SNUPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human SNUPN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNUPN
Additional Names:
Snurportin-1, RNA U transporter 1, SNUPN, RNUT1, SPN1
Protein Accession Number:
O95149
Ncbi Gene Id Number:
10073
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The nuclear import of the spliceosomal snRNPs U1, U2, U4and U5, is dependent on the presence of a complex nuclearlocalization signal. The latter is composed of the5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the UsnRNA and the Sm core domain. The protein encoded by this geneinteracts specifically with m3G-cap and functions as ansnRNP-specific nuclear import receptor. Alternatively splicedtranscript variants encoding the same protein have been identifiedfor this gene.
Background Reference 1:
Goette, M., et al. Biophys. J. 97(2):581-589(2009)
Background Reference 2:
Monecke, T., et al. Science 324(5930):1087-1091(2009)
Background Reference 3:
Ospina, J.K., et al. Mol. Biol. Cell 16(10):4660-4671(2005)
Background Reference 4:
Stelzl, U., et al. Cell 122(6):957-968(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-602

List Size:
400 ul

List Price:

$495.00

Datasheet
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