SNX1 Antibody

CATALOG NUMBER: 57-439

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This SNX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human SNX1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
59 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNX1
Additional Names:
Sorting nexin-1, SNX1
Protein Accession Number:
Q13596
Protein Gi Number:
17380569
Ncbi Gene Id Number:
6642
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellulartrafficking. This endosomal protein regulates the cell-surfaceexpression of epidermal growth factor receptor. This protein alsohas a role in sorting protease-activated receptor-1 from earlyendosomes to lysosomes. This protein may form oligomeric complexeswith family members. This gene results in three transcript variantsencoding distinct isoforms.
Background Reference 1:
Nisar, S., et al. Traffic 11(4):508-519(2010)
Background Reference 2:
Mari, M., et al. Traffic 9(3):380-393(2008)
Background Reference 3:
Bryant, D.M., et al. J. Cell. Sci. 120 (PT 10), 1818-1828 (2007) :
Background Reference 4:
Rojas, R., et al. Mol. Cell. Biol. 27(3):1112-1124(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-439

List Size:
400 ul

List Price:

$495.00

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