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Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.

SNX13 Antibody

CATALOG NUMBER: 56-298

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
112 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNX13
Additional Names:
Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
Protein Accession Number:
Q9Y5W8
Protein Gi Number:
24418867
Ncbi Gene Id Number:
23161
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a PHOX domain- and RGS domain-containingprotein that belongs to the sorting nexin (SNX) family and theregulator of G protein signaling (RGS) family. The PHOX domain is aphosphoinositide binding domain, and the SNX family members areinvolved in intracellular trafficking. The RGS family members areregulatory molecules that act as GTPase activating proteins for Galpha subunits of heterotrimeric G proteins. The RGS domain of thisprotein interacts with G alpha(s), accelerates its GTP hydrolysis,and attenuates G alpha(s)-mediated signaling. Overexpression ofthis protein delayes lysosomal degradation of the epidermal growthfactor receptor. Because of its bifunctional role, this protein maylink heterotrimeric G protein signaling and vesicular trafficking.
Background Reference 1:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 2:
Hillman, R.T., et al. Genome Biol.(2), R8 (2004) :
Background Reference 3:
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Background Reference 4:
Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-298

List Size:
400 ul

List Price:

$495.00

Datasheet
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