SNX15 Antibody

CATALOG NUMBER: 58-666

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SNX15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human SNX15.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
38 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNX15
Additional Names:
Sorting nexin-15, SNX15
Protein Accession Number:
Q9NRS6
Protein Gi Number:
13124562
Ncbi Gene Id Number:
29907
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellulartrafficking. Overexpression of this gene results in a decrease inthe processing of insulin and hepatocyte growth factor receptors totheir mature subunits. This decrease is caused by themislocalization of furin, the endoprotease responsible for cleavageof insulin and hepatocyte growth factor receptors. This protein isinvolved in endosomal trafficking from the plasma membrane torecycling endosomes or the trans-Golgi network. This gene encodestwo transcript variants encoding distinct isoforms. [provided byRefSeq].
Background Reference 1:
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Background Reference 2:
Phillips, S.A., et al. J. Biol. Chem. 276(7):5074-5084(2001)
Background Reference 3:
Barr, V.A., et al. Traffic 1(11):904-916(2000)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-666

List Size:
400 ul

List Price:

$495.00

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