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Western blot analysis in 293 cell line lysates (35ug/lane).
SOCS6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in 293 cell line lysates (35ug/lane).

SOCS6 Antibody

CATALOG NUMBER: 57-489

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SOCS6
Additional Names:
Suppressor of cytokine signaling 6, SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4, SOCS6, CIS4, SOCS4
Protein Accession Number:
O14544
Ncbi Gene Id Number:
9306
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene contains a SH2 domain anda CIS homolog domain. The protein thus belongs to thecytokine-induced STAT inhibitor (CIS), also known as suppressor ofcytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI),protein family. CIS family members are known to becytokine-inducible negative regulators of cytokine signaling. Theexpression of this gene can be induced by GM-CSF and EPO inhematopoietic cells. A high expression level of this gene was foundin factor-independent chronic myelogenous leukemia (CML) anderythroleukemia (HEL) cell lines.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Choi, Y.B., et al. J. Biol. Chem. 285(10):7271-7280(2010)
Background Reference 4:
Lai, R.H., et al. Gene 448(1):64-73(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-489

List Size:
400 ul

List Price:

$495.00

Datasheet
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