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Soluble TRAIL Receptor-2 Recombinant Protein

CATALOG NUMBER: 40-310

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES
Biological Activity:
Determined by its ability to inhibit apoptosis induced by Human sTRAIL/Apo2L in LN-18 cells (human glioblastoma cells).
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Soluble TRAIL Receptor-2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Soluble TRAIL Receptor-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Soluble TRAIL Receptor-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TNFRSF10B
Additional Names:
DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5, DR5, UNQ160/PRO186, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TRAIL receptor 2
Protein Accession Number:
NP_003833.4
Protein Gi Number:
224494019
Ncbi Gene Id Number:
8795
Background:
TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L. Recombinant human soluble TRAIL Receptor-2/DR5 is a 14.9 kDa protein (133 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-310

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
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