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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

SOSTDC1 Antibody

CATALOG NUMBER: 59-173

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This SOSTDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the C-terminal region of human SOSTDC1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SOSTDC1
Additional Names:
Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Ectodin, Uterine sensitization-associated gene 1 protein, USAG-1, SOSTDC1, USAG1
Protein Accession Number:
Q6X4U4
Protein Gi Number:
62287504
Ncbi Gene Id Number:
25928
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the sclerostin family and encodesan N-glycosylated, secreted protein with a C-terminal cystineknot-like domain. This protein functions as a bone morphogeneticprotein (BMP) antagonist. Specifically, it directly associates withBMPs, prohibiting them from binding their receptors, therebyregulating BMP signaling during cellular proliferation,differentiation, and programmed cell death.
Background Reference 1:
Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
Background Reference 2:
Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)
Background Reference 3:
Blish, K.R., et al. Mol. Biol. Cell 19(2):457-464(2008)
Background Reference 4:
Lamesch, P., et al. Genomics 89(3):307-315(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-173

List Size:
400 ul

List Price:

$495.00

Datasheet
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