SOX8 Antibody

CATALOG NUMBER: 58-610

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SOX8
Additional Names:
Transcription factor SOX-8, SOX8
Protein Accession Number:
P57073
Protein Gi Number:
10720294
Ncbi Gene Id Number:
30812
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the SOX (SRY-relatedHMG-box) family of transcription factors involved in the regulationof embryonic development and in the determination of the cell fate.The encoded protein may act as a transcriptional activator afterforming a protein complex with other proteins. This protein may beinvolved in brain development and function. Haploinsufficiency forthis protein may contribute to the mental retardation found inhaemoglobin H-related mental retardation (ART-16 syndrome).
Background Reference 1:
Nonaka, D. Am. J. Clin. Pathol. 131(5):731-736(2009)
Background Reference 2:
Hoff, S., et al. J. Comp. Neurol. 509(4):356-371(2008)
Background Reference 3:
Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Background Reference 4:
Schepers, G., et al. J. Biol. Chem. 278(30):28101-28108(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-610

List Size:
400 ul

List Price:

$495.00

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