SP2 Antibody

CATALOG NUMBER: 56-861

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-526 amino acids from the C-terminal region of human SP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SP2
Additional Names:
Transcription factor Sp2, SP2, KIAA0048
Protein Accession Number:
Q02086
Protein Gi Number:
119370531
Ncbi Gene Id Number:
6668
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the Sp subfamily of Sp/XKLFtranscription factors. Sp family proteins are sequence-specificDNA-binding proteins characterized by an amino-terminaltrans-activation domain and three carboxy-terminal zinc fingermotifs. This protein contains the least conserved DNA-bindingdomain within the Sp subfamily of proteins, and its DNA sequencespecificity differs from the other Sp proteins. It localizesprimarily within subnuclear foci associated with the nuclearmatrix, and can activate or in some cases repress expression fromdifferent promoters.
Background Reference 1:
Ito, H., et al. Biochim. Biophys. Acta 1789 (11-12), 681-690 (2009) :
Background Reference 2:
Wheeler, H.E., et al. PLoS Genet.(10), E1000685 (2009) :
Background Reference 3:
Letourneur, M., et al. Mol. Immunol. 46 (11-12), 2151-2160 (2009) :
Background Reference 4:
Sun, J.M., et al. J. Biol. Chem. 282(45):33227-33236(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-861

List Size:
400 ul

List Price:

$495.00

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