SPANXE Antibody

CATALOG NUMBER: 60-307

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SPANXE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human SPANXE.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
11 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SPANXE
Additional Names:
Sperm protein associated with the nucleus on the X chromosome E, Nuclear-associated protein SPAN-Xe, SPANX-E, SPANX family member E, SPANXE
Protein Accession Number:
Q8TAD1
Protein Gi Number:
85543354
Ncbi Gene Id Number:
64663
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Temporally regulated transcription and translation ofseveral testis-specific genes is required to initiate the series ofmolecular and morphological changes in the male germ cell lineagenecessary for the formation of mature spermatozoa. This gene is amember of the SPANX family of cancer/testis-associated genes, whichare located in a cluster on chromosome X. The SPANX genes encodedifferentially expressed testis-specific proteins that localize tovarious subcellular compartments. This particular gene encodes asperm protein that contains a consensus nuclear localization signalbut, although a role in spermatogenesis is suggested, the specificfunction of this family member has not yet been determined.
Background Reference 1:
Hansen, S., et al. Syst Biol Reprod Med 55, 18-26 (2010) :
Background Reference 2:
Kouprina, N., et al. Genome Res. 15(11):1477-1486(2005)
Background Reference 3:
Zendman, A.J., et al. Gene 309(2):125-133(2003)
Background Reference 4:
Westbrook, V.A., et al. Biol. Reprod. 64(1):345-358(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-307

List Size:
400 ul

List Price:

$495.00

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