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Western blot analysis in 293 cell line lysates (35ug/lane).
SPG7 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in 293 cell line lysates (35ug/lane).

SPG7 Antibody

CATALOG NUMBER: 56-453

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SPG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-141 amino acids from the Central region of human SPG7.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
88 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SPG7
Additional Names:
Paraplegin, 3424-, Spastic paraplegia 7 protein, SPG7, CAR, CMAR, PGN
Protein Accession Number:
Q9UQ90
Protein Gi Number:
116242796
Ncbi Gene Id Number:
6687
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a nuclear-encoded mitochondrialmetalloprotease protein that is a member of the AAA (ATPasesassociated with a variety of cellular activities) protein family.Members of this protein family share an ATPase domain and haveroles in diverse cellular processes including membrane trafficking,intracellular motility, organelle biogenesis, protein folding, andproteolysis. Two transcript variants encoding distinct isoformshave been identified for this gene. Mutations associated with thisgene cause autosomal recessive spastic paraplegia 7. [provided byRefSeq].
Background Reference 1:
Warnecke, T., et al. Mov. Disord. 25(4):413-420(2010)
Background Reference 2:
Augustin, S., et al. Mol. Cell 35(5):574-585(2009)
Background Reference 3:
Karlberg, T., et al. PLoS ONE(10), E6975 (2009) :
Background Reference 4:
Brugman, F., et al. Neurology 71(19):1500-1505(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-453

List Size:
400 ul

List Price:

$495.00

Datasheet
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