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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

SPINT2 Antibody

CATALOG NUMBER: 60-423

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SPINT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human SPINT2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SPINT2
Additional Names:
Kunitz-type protease inhibitor 2, Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin, SPINT2, HAI2, KOP
Protein Accession Number:
O43291
Ncbi Gene Id Number:
10653
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transmembrane protein with twoextracellular Kunitz domains that inhibits a variety of serineproteases. The protein inhibits HGF activator which prevents theformation of active hepatocyte growth factor. This gene is aputative tumor suppressor, and mutations in this gene result incongenital sodium diarrhea. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Dong, W., et al. Int. J. Cancer 127(7):1526-1534(2010)
Background Reference 2:
Bergum, C., et al. Prostate 70(13):1422-1428(2010)
Background Reference 3:
Sivagnanam, M., et al. Clin. Dysmorphol. 19 (1), 48 (2010) :
Background Reference 4:
Yamauchi, M., et al. Biol. Chem. 383(12):1953-1957(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-423

List Size:
400 ul

List Price:

$495.00

Datasheet
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