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Antibody used in IHC on Human kidney.
Antibody used in WB on Human Jurkat 1 ug/ml.
Antibody used in IHC on Human kidney.

SPPL2B Antibody

CATALOG NUMBER: 31-372

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPPL2B.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
SPPL2B antibody can be used for detection of SPPL2B by ELISA at 1:312500. SPPL2B antibody can be used for detection of SPPL2B by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
56 kDa, 65 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SPPL2B antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SPPL2B
Additional Names:
SPPL2B, IMP4, KIAA1532, MGC111084, PSL1, PSH4, IMP-4
Protein Accession Number:
NP_001070706
Protein Gi Number:
116734691
Ncbi Gene Id Number:
56928
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-372

List Size:
100 ul

List Price:

$519.00

Datasheet
Shipping Info

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