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Western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the detected SRD5A2 protein (arrow).
Western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the detected SRD5A2 protein (arrow).

SRD5A2 Antibody

CATALOG NUMBER: 61-971

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This SRD5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the Central region of human SRD5A2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SRD5A2
Additional Names:
3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR type 2, Steroid 5-alpha-reductase 2, S5AR 2, Type II 5-alpha reductase, SRD5A2
Protein Accession Number:
P31213
Protein Gi Number:
401056
Ncbi Gene Id Number:
6716
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a microsomal protein expressed at highlevels in androgen-sensitive tissues such as the prostate. Theencoded protein is active at acidic pH and is sensitive to the4-azasteroid inhibitor finasteride. Deficiencies in this gene canresult in male pseudohermaphroditism, specifically pseudovaginalperineoscrotal hypospadias (PPSH).
Background Reference 1:
Thigpen, A.E., et al. N. Engl. J. Med. 327(17):1216-1219(1992)
Background Reference 2:
Thigpen, A.E., et al. J. Clin. Invest. 90(3):799-809(1992)
Background Reference 3:
Labrie, F., et al. Endocrinology 131(3):1571-1573(1992)
Background Reference 4:
Andersson, S., et al. Nature 354(6349):159-161(1991)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-971

List Size:
400 ul

List Price:

$495.00

Datasheet
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